FDA approves West Nile test to screen blood

first_imgDec 2, 2005 (CIDRAP News) – A test to screen blood and organ donors for West Nile virus (WNV) has won approval by the Food and Drug Administration (FDA) after 2 years of trial use.The FDA yesterday announced approval of the Procleix West Nile virus assay, developed by Gen-Probe Inc., San Diego, and marketed by Chiron Corp., Emeryville, Calif. The test detects West Nile RNA in blood.The test has been used to screen more than 29 million units of donated blood since June 2003 and has detected the virus in more than 1,500 cases, preventing transfusion of contaminated blood into as many as 4,500 people, Gen-Probe officials said in a news release.The test is intended to help protect recipients of donated blood and organs from the virus. The FDA said there have been 30 cases in which people probably acquired WNV from a blood transfusion, and nine of the patients died.”This approval is the result of a tremendous cooperative effort among FDA, other public health agencies, the test kit manufacturers and the blood industry,” Jesse Goodman, MD, MPH, director of the FDA’s Center for Biologics Evaluation and Research, said in a news release.”To develop an investigational test to screen blood, tissue and organ donors, and to get this test in blood banks throughout the country, and then licensed this quickly is a remarkable achievement for public health and patient safety,” Goodman added.Another blood test is available to help doctors diagnose WNV, but it must be used in tandem with other laboratory tests, according to a Reuters report published yesterday. Procleix is the first approved test that stands alone, making it suitable for use by blood banks, the story said.Another WNV blood test, developed by Roche Molecular Systems, Inc., is still being used experimentally, Reuters reported. An FDA official said the agency is allowing Roche to use the test on a trial basis until it has enough data to apply for approval, the story said.Efforts to develop a WNV blood test began in 2002 when it was discovered that the virus could be transmitted in blood, the FDA said. With help from the FDA and other federal health agencies, biotechnology firms developed investigational tests that were quickly adopted on a trial basis. A total of about 1,600 infected donations were detected by the investigational tests, the FDA said.Close to 20,000 cases of WNV illness, with 762 deaths, have occurred in the United States since the virus first arrived in 1999, the FDA said.See also:FDA news release about WNV blood testhttp://www.fda.gov/NewsEvents/Newsroom/PressAnnouncements/2005/ucm108523.htmApr 8, 2004, CIDRAP News story “Six West Nile cases in 2003 linked to donated blood”last_img read more

Tony Pulis concedes life at West Brom has been hard for Rickie Lambert

first_img The striker moved from Liverpool for around £3million in the summer to revive his career but has started just three Barclays Premier League games. He has netted just once – a penalty – for the Baggies and is likely to be on the bench again for his Anfield return on Sunday. Lambert left Merseyside because of a lack of first-team opportunities just a year after joining from Southampton but has been kept out of the Baggies side by £12m record buy Rondon. Pulis said: “Rickie is knocking on my door all the time. He wants to play. It’s difficult at times because I understand he wants to play. “It’s about trying to find the right formation and shape for the team and trying to get the balance right. “In the back of our mind we were looking to bring him on against Tottenham (a 1-1 draw last Saturday) but we played so well, we were thinking ‘who do we bring off?’ “We didn’t think we would get Salomon right up to the last minute. Salomon was a real coup for us in lots of ways.” Meanwhile Pulis admits he is frustrated at the length of time it is taking Ben Foster to recover from a knee injury. The keeper damaged his cruciate knee ligament in March but is yet to return after a set-back in September. He added: “I am a typical manager, you want your players fit as quickly as you can get them and when they’re not fit you can get annoyed. “You just want players fit but the medical people here do a good job.” Boss Tony Pulis admits Rickie Lambert has suffered from West Brom’s last-ditch deal to sign Salomon Rondon.center_img Press Associationlast_img read more

Rory MacDonald tale of the tape: Career record, highlights, age, height

first_imgMacDonald’s mission when he signed with Bellator was to become a world champion. It was a close fight that would be decided after the fifth round. Lima spent all his energy in previous rounds, and MacDonald found an extra gear to propel him to his first-ever world title. Bellator welterweight champion Rory MacDonald is one of the premier welterweights in the world.The 29-year-old from Kelowna, British Columbia, Canada started MMA training at the age of 14 and made his professional debut at 16, defeating Terry Thiara by first-round submission at Extreme Fighting Challenge 4 in October 2005.  From there, MacDonald hasn’t looked back. He went undefeated in his first nine fights when he received a call to make his UFC debut at 20-year-old against Mike Guymon in January 2010. MacDonald won by first-round submission and didn’t look back by going 8-4 inside the Octagon. He beat the likes of Nate Diaz and former UFC champions B.J. Penn and Tyron Woodley.Join DAZN and watch Bellator 220 plus more than 100 fight nights a yearWhat MacDonald is remembered most for during his UFC run was back at UFC 189 in July when he challenged then-welterweight titlist, Robbie Lawler. For 21 minutes, MacDonald and Lawler slung the heavy leather in one of the most violent fights in MMA history. Lawler won by fifth-round TKO, but MacDonald cemented himself on that evening as one of the best welterweights in the world.Wanting a change in scenery, “The Red King” signed with Bellator in the summer of 2016. After demolishing Paul Daley at Bellator 179, MacDonald battled Douglas Lima for the welterweight title at Bellator 192 in January 2018. MacDonald came out on top in a war of attrition by unanimous decision to win the first world championship of his career.MacDonald returns to the cage for the first time in 2019, as he defends the title against Jon Fitch in the opening round of the Bellator welterweight grand prix at Bellator 220.Rory MacDonald tale of the tape: Age, height, bioBirth name: Rory MacDonaldBirthday: July 22, 1989Age: 29Birthplace: Kelowna, British Columbia, CanadaNationality: CanadianDivision: WelterweightHeight: 5-foot-11Reach: 76 inchesStance: OrthodoxTotal Fights: 25Career record: 20-5Wins by knockout: 7World titles held (current):  Bellator welterweight champion (current)World titles held (past): King of the Cage lightweight championship, King of the Cage Canadian lightweight championshipLast fight: Loss via first-round TKO to Gegard Mousasi at Bellator 206 in September 2018.Next fight: Jon Fitch at Bellator 220 on April 27MORE ABOUT DAZN• Meet DAZN, the first dedicated live sports streaming service• What sports are live-streamed on DAZN?• How much does DAZN’s live sports streaming service cost?Notable career highlightsRory MacDonald vs. Terry ThiaraWhen kids turn 16, and they are getting ready to try and obtain a driver’s license. Not MacDonald, who took on Terry Thiara at Extreme Fighting Challenge 4 on October 15, 2005. MacDonald showed age is nothing more than a number, submitting Thiara in the first round. Rory MacDonald vs. Mike GuymonMacDonald had gone 9-0 on the regional circuit in Canada before getting the call from UFC officials to face Guymon at UFC Fight Night on January 11, 2010. UFC president Dana White always says the Octagon jitters are real when it comes to making your UFC debut. MacDonald didn’t get the message, as he submitted Guymon in the first round.Rory MacDonald vs. B.J. PennBy this point at UFC on Fox in December 2012, MacDonald was 4-1 but needed a signature win on his resume. Enter the former two-division champion and one of the all-time greats in MMA history. Could MacDonald pass his toughest test to date?MacDonald showed he was more than ready to answer the bell. He battered Penn from one side of the cage to the other to win a comfortable unanimous decision and earn what would then be the most significant victory of his career and cement himself as someone watch out for as a potential future world champion. Rory MacDonald vs. Robbie LawlerArguably the greatest fight in UFC championship history. MacDonald and Lawler went to war for 21 minutes, with neither willing to take a step back. The savage war of attrition may be pegged by a particular moment between Rounds 4 and 5 when Lawler lowered his head to spit out blood from the brutal fight. The two then stared each other down until they were told to go back to their respective corners. In the fifth round, MacDonald’s face had taken too much punishment. A lethal combination from Lawler sank MacDonald and broke his nose. It was a legendary scrap that will go down as one of the most brutal battles in the Octagon.Rory MacDonald vs. Douglas Limalast_img read more